Population bottlenecks and patterns of human polymorphism
نویسندگان
چکیده
منابع مشابه
Population bottlenecks and patterns of human polymorphism.
Fay and Wu (1999) examine a historical model in which a population quickly shrinks, stays small for some time, and then suddenly recovers its original population size, at which it stays until samples are drawn from it. This is a bottleneck model of the kind traditionally used in population genetics (Nei, Maruyama, and Chakraborty 1975); however, it is not the model that is most commonly conside...
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We review the anatomical and archaeological evidence for an early population bottleneck in humans and bracket the time when it could have occurred. We outline the subsequent demographic changes that the archaeological evidence of range expansions and contractions address, and we examine how inbreeding effective population size provides an alternative view of past population size change. This ad...
متن کاملBottlenecks, genetic polymorphism and speciation.
THIRTY years ago Takeo Maruyama, Ranajit Chakradominant selection can be much greater than that mainborty, and I published an article about the effects tained by mutation-selection balance, but that overdomof bottlenecks on genetic variation (Nei et al. 1975). This inant selection incurs a large genetic load (genetic death article was motivated by two controversies occurring in or fertility exc...
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What are they? They occur when a wild population is reduced to a small number of individuals, and then increases again. They are typically caused by an environmental change such as unusual climatic conditions, or, increasingly, the actions of humans, as in over-hunting and habitat destruction. But if the population size is restored, everything ends up fine, surely? No. The small population size...
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ژورنال
عنوان ژورنال: Molecular Biology and Evolution
سال: 1999
ISSN: 0737-4038,1537-1719
DOI: 10.1093/oxfordjournals.molbev.a026054